Another month, another collection of (hopefully) interesting medical publications. When trial results are too good to be true, think fraud? Sheldrick, K. Evidence of Fabricated Data in a Vitamin C trial by Paul E Marik et al in CHEST. Available at: https://kylesheldrick.blogspot.com/2022/03/evidence-of-fabricated-data-in-vitamin.html This is the first time I have ever […]
COVID
54 posts
My initial evidence update for Paxlovid (nirmatrelvir/ritonavir) contained exactly no evidence, because nothing was published, despite recommendations at that time from multiple organizations. Sadly, two years into the pandemic, a large portion of the medical community still seems willing to act based solely on drug company press releases. The EPIC-HR […]
Normal saline: The world’s worst murder weapon? Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J; PLUS Study Investigators and the Australian and New Zealand Intensive Care […]
This is part of the ongoing series of articles updating the evidence on current COVID-19 therapies. The rest of the series can be found here, and there is probably more to come. This article will cover the evidence for inhaled steroids in COVID-19. I already covered the evidence for budesonide […]
This is part of the ongoing series of articles updating the evidence on current COVID-19 therapies. The rest of the series can be found here, and there is more to come. This article will cover the evidence for fluvoxamine in COVID-19.
This is part of the ongoing series of articles updating the evidence on current COVID-19 therapies. The rest of the series can be found here, and there is more to come. This article will cover the evidence for Interleukin-6 receptor antagonists (tocilizumab or sarilumab) in COVID-19. This is a group […]
This is part of the ongoing series of articles updating the evidence on current COVID-19 therapies. The rest of the series can be found here, and there is more to come. This article will cover the evidence for remdesivir in COVID-19. Remdesivir (GS-5734) is an antiviral drug that was originally […]
It’s that time again. A roundup of the most interesting emergency medicine articles I have read in the last few months.
I have avoided COVID therapies for a while, because so many people are already covering the topic, and honestly I am a little sick of COVID. However, with the OMICRON wave, everyone seems to have questions about therapies for COVID, so a quick evidence review seems appropriate. This article will […]