I think there are some very interesting papers in here this month. There are a couple big RCTs, but if you aren’t in the mood for EBM right now, I suggest at least having a look at the final paper, and imagine yourself volunteering to participate.
EM literature (critical appraisals)
237 posts
Addictions are incredibly challenging to treat in the emergency department, although hopefully everyone has accumulated a few wins with suboxone over recent years, and so maintains at least a modicum of optimism. Methamphetamine is much less common around me, but the primary drug of abuse in many areas of the […]
It is almost impossible to summarize a year’s worth of medical research in a 15 minute talk, but given that limitation, here are the articles that I selected as the most interesting or important for this year’s North York General Emergency Medicine Update:
I have written fairly extensively about the management of high risk PE. Despite their growing popularity, I have remained quite skeptical of catheter directed therapies. If you are going to give a thrombolytic, my sense is that it is going to be just as effective if given through a peripheral […]
Although guidelines have long suggested higher blood pressure targets in spinal cord injury, that recommendation has never been based on high quality evidence. (Walters 2013; Sanchez 2020) (This is the first ever RCT.) We have a bad habit of treating numbers in medicine, and often making things worse. (Remember the […]
At this point, most people in the emergency medicine and critical care worlds just assume that balanced (ie, 1:1:1) transfusion is a proven intervention, and the focus has mostly moved on the the potential of whole blood. I am in an almost nonexistent minority when I argue that balanced transfusion […]
Classic medicine: running high cost RCTs that are too small to give real answers Préterre C, Gaultier A, Obadia M, Vignal C, Mourand I, Plat J, Sablot D, Gaudron M, Rodier G, Godeneche G, Urbanczyk C, Marc G, Massardier E, Adam S, Boulanger M, Marcel S, Mechtouff L, Ronzière T, […]
The big paper of the month: ketamine vs etomidate for RSI Casey JD, Seitz KP, Driver BE, et al. Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2025 Dec 9. doi: 10.1056/NEJMoa2511420. Epub ahead of print. PMID: 41369227 On its face, this is a […]
There are many different approaches to stable patients with atrial fibrillation who present to the emergency department. Personally, I have leaned towards electrical cardioversion over chemical cardioversion in patients in whom cardioversion is appropriate. In the places I work, it is usually faster and easier to get a patient sedated […]