Normal saline: The world’s worst murder weapon? Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J; PLUS Study Investigators and the Australian and New Zealand Intensive Care […]
normal saline
5 posts
I have discussed the ongoing battle between normal saline and ‘balanced fluids’ many times in the past. First, there was the SPLIT trial, a double blind cluster RCT of 2200 ICU patients that showed no difference between saline and Plasma-Lyte 148. (Young 2015) Next, we had the SMART trial, an […]
My morning ritual of reading articles over coffee has transformed somewhat, such that there is a lot more playing with an infant, and a lot less evidence based medicine. Although the coffee isn’t going anywhere, it is usually cold by the time I have a free moment to get to […]
Do you have strong opinions about normal saline? If so, you might need a hobby, but also this paper is for you. The BaSICS trial is a massive RCT with more than 10,000 patients comparing normal saline to a balanced crystalloid IV fluid.