A key scientific lesson that I have discussed numerous times on this blog is that the interpretation of any new study must be placed within the context of what is already known about the topic. Although there must be equipoise for medical research to be ethical, equipoise does not mean […]
tranexamic acid
10 posts
Last week we covered TXA for epistaxis. The NoPAC study kept with the recent tradition in TXA papers and showed no benefit. This week, we are going to look at another TXA RCT, but this time for the management of subarachnoid hemorrhage (SAH). In case you were worried, this paper […]
Everyone knows about the CRASH-2 trial. It is now a decade old. It doesn’t seem like it desperately needs a new blog post, but I think that understanding this trial is important when trying to interpret the results of the newer CRASH-3 or WOMAN trials, and other TXA research that […]
Hemoptysis can be scary. I covered the emergency medicine approach to massive hemoptysis in one of the early posts on First10EM. However, even when the hemoptysis is small volume, it can be quite distressing to patients and clinicians alike. This paper asks whether using nebulized tranexamic acid (or TXA) for […]
Welcome to another edition of the First1oEM articles of the month – a collection of my favorite reads from the emergency medicine literature. Location, location, location Drennan IR, Strum RP, Byers A et al. Out-of-hospital cardiac arrest in high-rise buildings: delays to patient care and effect on survival. Canadian Medical […]