The big paper of the month: ketamine vs etomidate for RSI Casey JD, Seitz KP, Driver BE, et al. Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2025 Dec 9. doi: 10.1056/NEJMoa2511420. Epub ahead of print. PMID: 41369227 On its face, this is a […]
overdiagnosis
7 posts
There is little doubt that the use of testing has increased dramatically in emergency medicine during my career. Between 2001 and 2010 the use of CT in emergency departments increased 3-fold (and the use of MRI increased 9-fold, but for some reason it is still almost impossible for me to […]
Vitamin C in sepsis: Don’t LOVIT Lamontagne F, Masse MH, Menard J, et al; LOVIT Investigators and the Canadian Critical Care Trials Group. Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit. N Engl J Med. 2022 Jun 23;386(25):2387-2398. doi: 10.1056/NEJMoa2200644. PMID: 35704292 This is a big […]
Overdiagnosis is a huge problem in emergency medicine. We know that we are over-diagnosing pulmonary embolism (PE), as the rate of diagnosis has dramatically increased over the decades, but the morbidity and mortality from the disease has remained unchanged. (In other words, although these patients might have a pulmonary embolism, […]
Another month, another collection of (hopefully) interesting medical publications. When trial results are too good to be true, think fraud? Sheldrick, K. Evidence of Fabricated Data in a Vitamin C trial by Paul E Marik et al in CHEST. Available at: https://kylesheldrick.blogspot.com/2022/03/evidence-of-fabricated-data-in-vitamin.html This is the first time I have ever […]
In this month’s edition of the research round-up, we have everything from Bayesian analysis to CPR in outer space. With that kind of range, hopefully I have found something interesting for every reader.
