Over the last few years, I have seen a steady increase in the number of non-inferiority trials being published. This makes some sense, as they generally require fewer participants, and are therefore cheaper and easier to run. However, it presents a problem, as most of us (including myself) don’t really […]
EBM
9 posts
I read a lot, but I am not very organized. Over the years, I have read thousands of papers about evidence based medicine and methodology. I frequently find myself wanting to share interesting papers with students, or cite them in my blog posts, but I forget where to find the […]
What is a p-value? You might be surprised to hear that the topic is hotly debated; that the mere mention of p-values can get a statistician more excited than a fat kid on Halloween. The p-value is a probability, but it is not the probability that most people think it […]
October 2020. A month that many have declared the worst of all time, but can it really be that bad if you are getting another edition of the research roundup, with all sorts of EBM goodness?
It is already August! Even in COVID times, the days just seem to fly by. If you are looking for something boring to stretch those precious minutes out, I have another collection of evidence based medicine for you…
TXA has been the darling drug of emergency medicine and critical care since the publication of the CRASH 2 trial back in 2010. CRASH 2 demonstrated a 1.5% decrease in mortality when TXA was given to trauma patients with significant bleeding. (CRASH 2 2010) These results led to the widespread […]
The PAMPer study (Sperry 2018) - Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock