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  • First10EM resuscitation plans
  • Evidence Based Medicine
    • Evidence Based Medicine Resources
    • Evidence Based Medicine is Easy
    • EBM bibliography
    • EBM deep dives
    • Critical Appraisals
  • Foohey’s Figures
  • Other
    • Videos
    • Quick Reference
  • About
    • Who am I and what is FOAM?
    • How to use First10EM (mental practice)
    • Disclaimer
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PEERLESS interventional therapies for pulmonary embolism

The decision between mechanical thrombectomy and catheter directed thrombolysis for pulmonary embolism is not one that most emergency physicians are making. Most (like me) probably don’t even have access to such therapies, which might be a good thing, as both therapies remain completely unproven. However, I thought I would share […]

PEERLESS: Interventional therapies for pulmonary embolism

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Research Roundup First10EM best of emergency medicine research

Do you change your practice when new evidence is published? Will these articles change your practice? Will you read them? Does anyone read them? I don’t know, but here is another month of my reading summarized.  For the regular readers, you will have noticed I have taken a few weeks […]

Research Roundup for January 2025

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Research Roundup First10EM best of emergency medicine research

Another month, another set of articles. Perhaps some are useful. Perhaps some will guide your practice. At least one should completely blow your mind.

The December 2024 Research Roundup

1 comment
Procalcitonin ADAPT SEPSIS trial

Antibiotic resistance is an existential problem. Optimizing sepsis care, including the appropriate length of antibiotic therapy, is an important goal. So should we be willing to allow an increase in mortality to reduce total antibiotic use, as the ADAPT-Sepsis non-inferiority design seems to imply?

Killer antibiotic stewardship strategy? (The ADAPT-Sepsis trial)

6 comments
Hyponatremia correction rate

When managing hyponatremia, the primary concern (at least as far as I have always been taught) is osmotic demyelination syndrome. We are warned not to correct the sodium too quickly, because the neurologic outcome can be awful. However, demyelination is very rare, and apparently there is a lot of data […]

Big practice change coming? How fast do you correct hyponatremia?

1 comment
Does TXA work for anything

Despite being widely talked about in glowing terms, the original WOMAN trial was clearly negative, with no benefit in their primary outcome, and no change in all cause mortality, and therefore no hint of benefit. (There is a lot of confusion about what disease specific mortality means when this paper […]

WOMAN-2: TXA has no role in postpartum hemorrhage

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The First10EM monthly wrap-up

The First10EM monthly wrap up is a place for me to share updates about the website, about my academic life, and also interesting content, such as books, podcasts, and other FOAMed, that I have encountered in the prior month (or now quarter). Obviously the format means the focus is mostly […]

The First10EM monthly wrap-up for autumn 2024

Research Roundup First10EM best of emergency medicine research

Back for another month of interesting, arcane, important, or baffling articles. As we enter the winter in the Northern hemisphere, and I have little interest in heading outside, I will probably spend more time reading, so these write ups might get longer for the next few months. For now, the […]

The November 2024 Research Roundup

3 comments
iv VERSUS io in cardiac arrest

In the most recent BroomeDocs podcast, we talk about an attempt to use the IM route to give cardiac arrest victims epinephrine faster. (The podcast and Research Roundups blog post might actually come out next week.) I was skeptical about the outcomes, partly because the evidence that epinephrine helps at […]

IV versus IO for cardiac arrest (PARAMEDIC3 and IVIO)

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