Myasthenic crisis

A guide to the resuscitation of myasthenic crisis in the emergency department.


A 50 year old woman presents with a 2 day history of dysuria, for which she was started on ciprofloxacin last night. Since this morning, she has become increasingly weak, and now finds it impossible to get out of bed. She called 911 when she noticed she couldn’t catch her breath. She wonders whether this might be related to her myasthenia gravis…

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Rapid Review: Myasthenia Gravis

A rapid review of the diagnosis and management of myasthenia gravis in the emergency department.

In the Rapid Review series, I briefly review the key points of a clinical review paper.

The topic: Myasthenia gravis

The paper: Spillane J, Higham E, Kullmann DM. Myasthenia gravis. BMJ (Clinical research ed.). 2012; 345:e8497. PMID: 23261848

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