Last year, the FDA granted andexanet alfa an accelerated approval as a reversal agent for factor Xa inhibitors, but based that decision on a complete lack of useable science. This decision is almost identical to the approval of idarucizumab, a debacle I have discussed previously. (At that time, I was chastised by Scott Weingart for … Continue reading Andexanet Alfa: More garbage science in the New England Journal of Medicine